Artemisiaside A: A new Lignan Glycoside and its Analogues From the Aerial Parts of <i>Artemisia argyi</i>-Reference-Cited by-同舟云学术

Artemisiaside A: A new Lignan Glycoside and its Analogues From the Aerial Parts of Artemisia argyi

Published:2022-08 Issue:8 Volume:17 Page:1934578X2211185
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Tong Chuan-Wang¹,Tao Ming²,Zhang En-Bo²,Huang Yi²,Geng Hao²^ORCID,Yu Yang³

Affiliation:

1. Wuhu Institute of Technology, Wuhu, PR China

2. Xichang University, Xichang, PR China

3. School of Pharmacy, Anhui University of Chinese Medicine, Hefei, PR China

Abstract

Chemical analysis of the aerial parts of Artemisia argyi H. Lév. & Vaniot led to the isolation of 6 lignans, including a new lignan glycoside, artemisiaside A, using various chromatographic techniques. Detailed spectroscopic (including 1D, 2D- nuclear magnetic resonance) and high resolution mass spectroscopy procedures, and electronic circular dichroism were used to ascertain the structural orientations of these compounds. The anti-inflammatory activities of compounds 1 to 6 were evaluated by measuring their inhibitory effects on lipopolysaccharide (LPS) -induced nitric oxide (NO) production in RAW264.7 LPS-activated macrophages. At 50 μM, compound 1 showed moderate anti-inflammatory activity with an inhibition rate of 61.2%.

Funder

Doctoral Scientific Research and Double High Talent Project of Xichang University

Key Research and Development Program of Science and Technology Bureau of Liangshan Yi Autonomous Prefecture

Natural Science Key Research Program of Anhui Province University

Foundation of Anhui Province Key Laboratory of Research & Development of Chinese Medicine

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X221118552

Reference22 articles.

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2. The Artemisia L. Genus: A Review of Bioactive Essential Oils

3. Extraction, Isolation and Characterization of Bioactive Compounds from Artemisia and Their Biological Significance: A Review

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