A New Diterpenoid with a Rearranged Skeleton from Salvia prattii-Reference-Cited by-同舟云学术

A New Diterpenoid with a Rearranged Skeleton from Salvia prattii

Published:2017-08 Issue:8 Volume:12 Page:1934578X1701200
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Kawabe Hiroshi¹,Suzuki Riyo¹,Hirota Hiroshi¹,Matsuzaki Keiichi²,Gong Xun³,Ohsaki Ayumi¹

Affiliation:

1. College of Humanities and Sciences, Nihon University, Setagaya-ku, Tokyo, Japan, 156-8550

2. School of Pharmacy, Nihon University, 7-7-1 Narashinodai, Funabashi, Chiba, Japan, 274-8885

3. Kunming Institute of Botany, Chinese Academy of Science, Kunming, China, 650204

Abstract

A new diterpenoid with a rearranged skeleton, prattinin A (1), was isolated along with five known compounds (2–6) from the roots of Salvia prattii. The structure of 1 bearing a methyl group at the C-5 position was established by extensive spectroscopic analyses and the absolute configuration of 1 was elucidated by comparing the calculated and experimental electronic circular dichroism (ECD) spectra. Compounds 1, 3, 4, and 5 exhibited moderate or weak cytotoxicity against HL-60 and HeLa cell lines.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1701200807

Reference12 articles.

1. Constituents from Salvia Species and Their Biological Activities

2. Diversity of Furanoeremophilanes in Major Ligularia Species in the Hengduan Mountains

3. Salviskinone A, a diterpene with a new skeleton from Salvia przewalskii

4. Two New Diterpenoids from Salvia Przewarskii

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