Constituents of Bulbs of three Species of the Hyacinthaceae (Hyacinthoideae): Eucomis vandermerwei, E. zambesiaca and Resnova humifusa-Reference-Cited by-同舟云学术

Constituents of Bulbs of three Species of the Hyacinthaceae (Hyacinthoideae): Eucomis vandermerwei, E. zambesiaca and Resnova humifusa

Published:2015-07 Issue:7 Volume:10 Page:1934578X1501000
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Sihra Jaspreet K.¹,Thumser Alfred E.²,Langat Moses K.¹³,Crouch Neil R.³⁴,Mulholland Dulcie A.¹³

Affiliation:

1. Department of Chemistry, Faculty of Engineering and Physical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK

2. Division of Biochemical Sciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK

3. School of Chemistry and Physics, University of KwaZulu-Natal, Durban, 4041, South Africa

4. Ethnobotnany Unit, National Botanical Institute, P.O. Box 52099, Berea Road, Durban, South Africa

Abstract

Phytochemical analyses of the bulbs of Eucomis vandermerwei and E. zambesiaca yielded homoisoflavonoids and triterpenoid derivatives. A new (17 S*,23 S*)-epoxy-3β,15β,29-trihydroxy-27-norlanost-8-en-24-one) was isolated from E. zambesiaca. Resnova humifusa yielded homoisoflavonoids, and a tetrahydropyran derivative, 2-methyl-3-(4 S*,5 R*,7 S*-trihydroxy-8 S*-hydroxymethyltetrahydro-6H-4-pyranyl)-2-propenoic acid. All compounds were assayed for COX-2 inhibition of cyclooxygenase; 3,5,7-trihydroxy-3-(4′-methoxybenzyl)-4-chromanone was found to have significant activity.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1501000718

Reference15 articles.

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3. Infraspecific chemical variation in Scilla zebrina (Hyacinthaceae)

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