A Literature Review of Meleagrins

Author:

El-Sawy Eslam R1ORCID,Abdel-Aziz Mohamed S2,Kirsch Gilbert3

Affiliation:

1. Chemistry of Natural Compounds Department, National Research Centre, Giza, Egypt

2. Microbial Chemistry Department, Biotechnology Research Institute, National Research Centre, Giza, Egypt

3. Laboratoire Lorrain de Chimie Moléculaire (L.2.C.M.), Université de Lorraine, Metz, France

Abstract

Fungal bioactive secondary metabolites are considered promising sources for the production of unique compounds with exceptional chemical structures. Of these bioactive secondary metabolites, meleagrins are prenylated indole alkaloids characterized by a triazaspirocyclic skeleton that is generally obtained from Penicillium species. Meleagrins are alkaloids with promising biological activities. Here is a survey of previously published research on meleagrins: their sources, biosynthetic pathways, synthesis, and bioactivities.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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