Isolation and Identification of Secondary Metabolites FromStreptomycessp. SP301

Author:

Liu Mengyujie1,Shi Peng2ORCID,Lu Chunhua3,Zhong Lihong1

Affiliation:

1. Department of Pharmacy, Qilu Hospital of Shandong University, Jinan, P.R. China

2. Key Laboratory of Microbial Technology, Shandong University, Qingdao, P.R. China

3. Key Laboratory of Chemical Biology (Ministry of Education), School of Pharmaceutical Science, Shandong University, Jinan, P.R. China

Abstract

Seven compounds, namely aminobenzoates A to D (1-4), naphthalenecarboxylates A and B (5-6), and glycosylatelactone A (7), were isolated from the fermentation medium of Streptomyces sp. SP301. Of these, aminobenzoates C and D (3-4), naphthalenecarboxylate B (6), and glycosylatelactone A (7) are new compounds. Aminobenzoates A to D (1-4) shared a common aromatic starter unit, para-aminobenzoic acid , and biosynthesis involving a different pathway. The structures were elucidated on the basis of 1D- and 2D-Nuclear Magnetic Resonance (NMR) spectroscopy and HR-ESIMS analysis.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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1. Bacterial terpenome;Natural Product Reports;2021

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