Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy-Reference-Cited by-同舟云学术

Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy

Published:2019-06 Issue:6 Volume:14 Page:1934578X1985822
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Wu Tao¹,Kwaku Osafo Raymond¹,Li Hai-Zhou¹,Yang Chong-Ren²,Ge Long-Jiao³,Xu Min¹

Affiliation:

1. Center for Pharmaceutical Sciences, Faculty of Life Science and Technology, Kunming University of Science and Technology, P.R. China

2. State Key Laboratory of Phytochemistry and Plant Resources of West China, Kunming Institute of Botany, Chinese Academy of Sciences, P.R. China

3. Translational Lab of Primate Brain Research, Kunming Institute of Zoology, Chinese Academy of Sciences, P.R. China

Abstract

The term ginseng refers to the dried roots of several plants belonging to the genus Panax of the Araliaceae family. The 3 major commercial ginsengs are Panax notoginseng (Burk.) F.H. Chen (Notoginseng), P. ginseng C.A. Meyer (Ginseng), and P. quinquefolius L. (American ginseng), which have been used as herbal medicines. Over 18,000 papers on ginsengs have been published on the basis of their structural diversity and biological activities. Many reviews have summarized the phytochemistry, pharmacology, and clinical use of ginsengs, but the structure-activity relationship (SAR) of ginsenosides from ginsengs in autophagy is unavailable. Herein, we review the structural diversity of ginsenosides, especially the ones in notoginseng, and the SAR in autophagic activity is discussed in detail.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X19858223

Reference79 articles.

1. China Brain Project: Basic Neuroscience, Brain Diseases, and Brain-Inspired Computing

2. Increase in apoptotic effect of Panax ginseng by microwave processing in human prostate cancer cells: in vitro and in vivo studies

3. Ginsenoside Rg3 attenuates sepsis-induced injury and mitochondrial dysfunction in liver via AMPK-mediated autophagy flux

4. Autophagy: a new pathway for traditional Chinese medicine

5. Icariin Promotes Angiogenic Differentiation and Prevents Oxidative Stress-Induced Autophagy in Endothelial Progenitor Cells

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