Simultaneous Identification of Characteristic Components in HPLC-PDA-ELSD Fingerprint Profile of Ginkgo biloba Leaves Extract

Abstract

This is an updated fingerprint profile for the simultaneous identification of 29 compounds, mainly including characteristic -terpene trilactones and flavonoid glycosides from Ginkgo biloba leaves (EGb) by employing a high-performance liquid chromatography-photodiode array-evaporative light scattering detector method. Compounds 1 and 6 had not been previously either detected or described in any EGb samples. In general, these 29 compounds were distributed into 5 regions in the fingerprint according to their different structural properties. This efficient analytical method could be generally applied to the quality control of EGb761 and other commercially available EGb products in the Chinese active pharmaceutical ingredients market.