A New Oxoaporphine Alkaloid from the Root of Dasymaschalon glaucum-Reference-Cited by-同舟云学术

A New Oxoaporphine Alkaloid from the Root of Dasymaschalon glaucum

Published:2018-11 Issue:11 Volume:13 Page:1934578X1801301
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Silprakob Weerachai¹,Sukhamsri Nuntaporn²,Kuhakarn Chutima²,Hongthong Sakchai²,Jariyawat Surawat³,Suksen Kanoknetr³,Akkarawongsapat Radeekorn⁴,Limthongkul Jitra⁴,Nantasaen Narong⁵,Reutrakul Vichai²

Affiliation:

1. Division of Chemistry, School of Science, University of Phayao, Mae Ka, Muang, Phayao 56000, Thailand

2. Department of Chemistry, and Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University, Bangkok 10400, Thailand

3. Department of Physiology, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand

4. Department of Microbiology, Faculty of Science, Mahidol University, Rama 6 Road, Bangkok 10400, Thailand

5. The Forest Herbarium National Park, Wildlife and Plant Conservation Department, Ministry of Natural Resources and Environment, Chatuchak, Bangkok 10900, Thailand

Abstract

The first phytochemical investigation of the root of Dasymaschalon glaucum led to the isolation of a new oxoaporphine alkaloid 1 together with seven known compounds, duguevalline (2), stigmalactam (3), enterocarpam III (4), desmosdumotin B (5), spiraeamide (6), kaempferol-3- O-glucopyranoside (7) and β-sitosterol (8). The chemical structures of all isolated compounds were established on the basis of their spectroscopic data. The cytotoxic and anti-HIV 1-RT activities of isolated compounds were also evaluated.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1801301115

Reference18 articles.

1. The Genus Dasymaschalon (Annonaceae) in Thailand

2. Dasytrichone, A Novel Flavone From Dasymaschalon Trichophorum With Cancer Chemopreventive Potential

3. Total synthesis and bioactivity of unique flavone desmosdumotin B and its analogs

4. Polyoxygenated cyclohexene derivatives isolated from Dasymaschalon sootepense and their biological activities

5. A New Neolignan, and the Cytotoxic and Anti-HIV-1 Activities of Constituents from the Roots of Dasymaschalon sootepense