Affiliation:
1. Faculty of Life Science and Technology, Kunming University of Science and Technology, P.R. China
Abstract
Flavescensin A (1), a novel rearrangement derivative of pterocarpan with an unusual spirotetrahydrofuran ring, along with 7 known pterocarpans were isolated from the roots of Sophora flavescens using several different chromatographic separations. The planar structure of 1 was elucidated by their nuclear magnetic resonance spectroscopic and high-resolution electrospray ionization mass spectrometry data, and the absolute configuration of 1 was determined on the basis of electronic circular dichroism data. Putative biosynthetic pathway toward 1 was proposed. In addition, all of the compounds were evaluated for their anti-influenza virus and anti-inflammatory activities.
Funder
National Natural Science Foundation of China
Yunnan innovation team
china postdoctoral science foundation
Subject
Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine
Cited by
1 articles.
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