Aspidosperma-type Alkaloids from Melodinus Suaveolens

Author:

Zhang Jian1,Song Min1,Liu Zhi-Wen1,Xiao Hua1,Fan Chun-Lin1,Zhang Xiao-Qi1,Ye Wen-Cai1

Affiliation:

1. Institute of Traditional Chinese Medicine & Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, People's Republic of China

Abstract

Three new aspidosperma-type alkaloids, 3-oxo-11-hydroxytabersonine (2), 11-hydroxytabersonine N-oxide (3) and 11-methoxytabersonine N-oxide (4), along with three known ones were isolated from the twigs and leaves of Melodinus suaveolens. The structures of the new compounds were elucidated by using spectroscopic methods, and circular dichroism experiments. The known compounds were identified by comparing their spectroscopic data with those reported in the literature.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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