Crocetenone, a New Rotenoid with an Unusual trans-fused Ring System from Iris crocea

Author:

Bhat Gulzar A.12,Mir Fauzia1,Shawl Abdul S.1,Ganai Bashir A.23,Kamili Azra N.3,Masood Akbar2,Tantry Mudasir A.3

Affiliation:

1. Natural Products Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Srinagar, Kashmir 190005, India

2. Department of Biochemistry, University of Kashmir, Srinagar, Kashmir 190006, India

3. Phytochemistry Laboratories, Centre of Research for Development, University of Kashmir, Srinagar, Kashmir 190006, India

Abstract

Crocetenone, a new rotenoid (1), along with five known compounds apocyanin (2), tectorigenin (3), 5,2′,3′-trihydroxy-7-methoxy flavanone (4), tectoridin (5) and tectoridin glycoside (6), were isolated from the methanolic extract of the root of Iris crocea. The structure of compounds was elucidated on the basis of 1D- and 2D-NMR spectroscopic and MS analysis. Antibacterial and antioxidant activities of compounds 1-6 were evaluated. Crocetenone (1) showed a prominent antibacterial activity.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Reference16 articles.

1. Secondary metabolites of the choosen genus iris species

2. ChopraRN NayarSL ChopraIC. (1956) Glossary of Indian Medicinal Plants, CSIR, Publication, New Delhi.

3. Isoflavonoids from Iris crocea

4. Irispurinol, A 12a-hydroxyrotenoid from Iris spuria

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