A New Pimarane-type Diterpenoid from the Seeds of Bowdichia virgilioides

Author:

Kubo Miwa1,Uemura Misao1,Harada Kenichi1,Ohsaki Ayumi2,Fukuyama Yoshiyasu1

Affiliation:

1. Faculty of Pharmaceutucal Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan

2. College of Humanities and Sciences, Nihon University, 3-25-40 Sakurajosui Setagaya-Ku, Tokyo 156-8550, Japan

Abstract

A new pimarane-type diterpenoid, sucupiol (1), and nine known furanocassane-type diterpenoids, vouacapane (2), 7β-hydroxyvouacapane (3), 7β-acetoxyvouacapane (4), 6α-hydroxyvouacapane (5), 6α-acetoxyvouacapane (6), sucutinirane F (7), sucutinirane E (8), 6α, 7β-diacetoxyvouacapane (9), and 6α, 7β-diacetoxyvouacapane-14β-al (10), were isolated from the seeds of Bowdichia virgilioides and their structures were elucidated by using 2D NMR data. The isolation of 1 provides evidence to support the presence of intermediate A in the course of biosynthesis of furanocassane-type diterpenoids.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

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