Alkaloids from the Tuber of Stephania cf. rotunda-Reference-Cited by-同舟云学术

Alkaloids from the Tuber of Stephania cf. rotunda

Published:2016-07 Issue:7 Volume:11 Page:1934578X1601100
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Le Duy Hoang¹²,Nishimura Katsumi¹,Tanahashi Takao¹

Affiliation:

1. Department of Organic Chemistry, Kobe Pharmaceutical University, Kobe 658-8558, Japan

2. Pham Van Dong University, Quang Ngai Province, Vietnam

Abstract

Chemical investigation of the tuber of Stephania cf. rotunda collected in Vietnam led to the isolation of a new stephaoxocane-type alkaloid, stepharotudine (1), twenty-eight known alkaloids, and two known amides. The chemical structures of the isolated compounds were determined by spectroscopic and chemical methods. The absolute configuration of the new compound was determined from its CD spectrum and by 1H NMR analyses of its MPA esters. For the known alkaloids (-)-crebanine-β- N-oxide (2), uthongine (3), and palmatrubine (4), fully assigned NMR data are also reported for the first time.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1601100720

Reference21 articles.

1. LoiDT. (2004) Glossary of Vietnamese Medicinal Plants and Drugs (in Vietnamese). Medical Publisher, Ha Noi, Vietnam, 779–782;

2. PerryLM. (1980) Medicinal Plants of East and Southeast Asia, attributed properties and uses. Cambridge, the M.I.T. Press, 268

3. HoPH. (2003) An illustrated flora of Vietnam (in Vietnamese), Vol. 1, Youth Publisher, HCMC, Vietnam, 337–338.

4. The genus Stephania (Menispermaceae): Chemical and pharmacological perspectives