Triterpenoids from Anthocleista grandiflora (Gentianaceae)

Author:

Magadula Joseph J.12,Mulholland Dulcie A.13,Crouch Neil R.14

Affiliation:

1. Natural Products Research Group, School of Chemistry, University of KwaZulu-Natal, Durban 4041, South Africa

2. Institute of Traditional Medicine, Muhimbili University of Health and Allied Sciences, P.O. Box 65001, DSM, Tanzania

3. Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK

4. Ethnobotany Unit, South African National Biodiversity Institute, P.O. Box 52099, Berea Road 4007, Durban, South Africa

Abstract

The stem bark of Anthocleista grandiflora (Gentianaceae) has yielded five triterpenoids, baruol, 3-deacetylmongolenin, anthocleistone, 6-ketoanthocleistone and lupenone together with scopoletin and (+)-de- O-methyllasiodiplodin. 3-Deacetyl-mongolenin was isolated from the leaves while the root bark yielded, in addition to the above compounds, the secoiridoid, sweroside.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Reference17 articles.

1. PalmerE, PitmanN. (1972) Trees of southern Africa. Volume 3, AA. Balkema, Cape Town, pp. 1845–1847.

2. Drug Plants of Africa

3. WattJM, Breyer-BrandwijkMG. (1962) The medicinal and poisonous plants of southern and eastern Africa. E. & S. Livingstone Ltd., Edinburgh and London, p. 727.

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