Prenylhydroquinone-Derived Secondary Metabolites from Cultures of the Basidiomycete Lentinus Similis BCC 52578-Reference-Cited by-同舟云学术

Prenylhydroquinone-Derived Secondary Metabolites from Cultures of the Basidiomycete Lentinus Similis BCC 52578

Published:2015-08 Issue:8 Volume:10 Page:1934578X1501000
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Isaka Masahiko¹,Palasarn Somporn¹,Sappan Malipan¹,Srichomthong Kitlada¹,Karunarathna Samantha C.²³⁴⁵⁶,Hyde Kevin D.²³⁴⁵⁶

Affiliation:

1. National Center for Genetic Engineering and Biotechnology (BIOTEC), 113 Thailand Science Park, Phaholyothin Road, Klong Luang, Pathumthani 12120, Thailand

2. School of Science, Mae Fah Luang University, Chiang Rai 57100, Thailand

3. Institute of Excellence in Fungal Research, Mae Fah Luang University, Chiang Rai, 57100, Thailand

4. Key Laboratory of Economic Plants and Biotechnology, Kunming Institute of Botany, Chinese Academy of Sciences, 132 Lanhei Road, Kunming 650201, China

5. World Agroforestry Centre, China & East-Asia Office, 132 Lanhei Road, Kunming 650201, China

6. Mushroom Research Foundation, 128 M.3 Ban Pa Deng T. Pa Pae, A. Mae Taeng, Chiang Mai 50150, Thailand.

Abstract

Two new prenylhydroquinone-derived compounds, lentinospirol (1) and 1-(2,5-dihydroxyphenyl)-4-hydroxy-3-methyl-1-butanone (2), were isolated from cultures of the basidiomycete Lentinus similis BCC 52578, together with the known compounds panepoxydone (3), panepoxydione (4), isopanepoxydone (5), 2,2-dimethyl-6-hydroxy-2 H-chromene (6), and (3 R,4 S)-3,4-dihydroxy-2,2-dimethyl-6-methoxychroman (7). Compounds 3 and 4 exhibited cytotoxicity against all cell-lines tested, while the other compounds were inactive.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1501000820

Reference18 articles.

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4. Lactarane Type Sesquiterpenoids as Inhibitors of Leukotriene Biosynthesis and Other, New Metabolites from Submerged Cultures of Lentinellus cochleatus (Pers. ex Fr.) Karst

5. Chromanones from Lentinus crinitus (Basidiomycetes)

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