Comparative Chemical Study and Cytotoxic Activity of Uvariodendron angustifolium Essential Oils from Benin-Reference-Cited by-同舟云学术

Comparative Chemical Study and Cytotoxic Activity of Uvariodendron angustifolium Essential Oils from Benin

Published:2014-02 Issue:2 Volume:9 Page:1934578X1400900
ISSN:1934-578X
Container-title:Natural Product Communications
language:en
Short-container-title:Natural Product Communications

Author:

Noudogbessi Jean-Pierre¹,Gary-Bobo Magali²,Adomou Aristide³,Adjalian Elvis¹,Alitonou Guy Alain¹,Avlessi Félicien¹,Garcia Marcel²,Sohounhloue Dominique C. K.¹,Menut Chantal²

Affiliation:

1. Université d'Abomey-Calavi, Ecole Polytechnique d'Abomey-Calavi, Laboratoire d'Etude et de Recherche en Chimie Appliquée (LERCA), 01 BP 2009 Cotonou, Benin

2. Institut des Biomolécules Max Mousseron, UMR 5247, Equipe « Glyco et nanovecteurs pour le ciblage thérapeutique », Faculté de Pharmacie, 15 Avenue Charles Flahault, BP 14491, 34093 Montpellier, France

3. Herbier National, Département de Botanique, Faculté des Sciences et Techniques, Université d'Abomey-Calavi, République du Bénin

Abstract

This study aimed to compare the chemical composition of volatile extracts obtained by hydrodistillation of leaves, stems, bark and roots of Uvariodendron angustifolium (Engl. & Diels) R. E. Fries. The essential oils, obtained with yields between 0.12 and 0.66%, were analyzed by GC/FID and GC/MS. A great variability in the chemical composition was observed depending on the plant part treated. The essential oils obtained from leaves and stems contained mainly neral (29.7–30.5%) and geranial (42.9–47.3%), while methyl eugenol was the major component of the volatile extracts from bark (68.3%) and roots (85.3%). Interesting cytotoxic properties of these essential oils on human breast cancer cells MCF-7 were demonstrated.

Publisher

SAGE Publications

Subject

Complementary and alternative medicine,Plant Science,Drug Discovery,Pharmacology,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/1934578X1400900232

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