Xp11.2 translocation renal cell carcinoma with osseous metaplasia

Abstract

Xp11.2 translocation renal cell carcinoma is an uncommon and distinctive subtype of renal neoplasm. Osseous metaplasia with renal cell carcinoma is extremely rare and only less than 20 cases have been reported in the literature distinctly in clear cell, papillary and chromophobe subtypes. There has only been one report of Xp11.2 translocation renal cell carcinoma with osseous metaplasia in an elderly woman. We present the first case of this unusual renal neoplasm associated with osseous metaplasia in an adolescent male with no history of previous exposure to chemotherapy who presented with symptomatic anemia due to painless haematuria. Level of evidence: Level 4.