A ‘real-world’ standard for radical prostatectomy: Analysis of the British Association of Urological Surgeons Complex Operations Reports, 2016–2018

Author:

John Joseph B1ORCID,Pascoe John1,Fowler Sarah2,Walton Thomas3,Johnson Mark4,Aning Jonathan5ORCID,Challacombe Benjamin6,Bufacchi Rory78,Dickinson Andrew J9,McGrath John S1

Affiliation:

1. Royal Devon and Exeter NHS Foundation Trust, UK

2. The British Association of Urological Surgeons, UK

3. Nottingham University Hospitals NHS Trust, UK

4. The Newcastle Upon Tyne Hospitals NHS Foundation Trust, UK

5. North Bristol NHS Trust, UK

6. Guy’s and St Thomas’ NHS Foundation Trust, UK

7. Italian Institute of Technology, Italy

8. Department of Neuroscience, Physiology and Pharmacology, University College London (UCL), UK

9. University Hospitals Plymouth NHS Trust, UK

Abstract

Objective: To produce comprehensive and detailed benchmarking data allowing surgeons and patients to compare practice against, by using all recorded radical prostatectomies across a 3-year period in England. Patients and methods: The British Association of Urological Surgeons (BAUS) manages the radical prostatectomy (RP) Complex Operations Database. Surgical departments upload data which they can review and amend before lockdown and data cleansing. Analysis of 2016–2018 data held on the BAUS Complex Operations Database was performed for 21,973 patients undergoing RP in England, producing procedure-specific benchmarking data. General linear models were used to assess differences in patient selection between different operative modalities. Analysis involved assessment of case selection, operative decisions and outcomes, case volume and pathological outcomes. Results: Using national Hospital Episode Statistics, the BAUS RP dataset was estimated 91% complete. Median age was 65 and 96% were American Society of Anesthesiologists (ASA) Grades 1–2. Over 80% had RP performed in a high-volume centre (>100 annual RPs) and 88% had Gleason grade group (GGG) ⩾2 disease on biopsy. Robotic-assisted RP (RARP), laparoscopic RP (LRP) and open RP (ORP) were performed in 85%, 7.2% and 7.7% of cases, respectively. Patient and disease characteristics differed across surgical modalities. Transfusion rates were 0.14% in RARP, 0.38% in LRP and 1.8% in ORP. Increased positive surgical margin (PSM) rates were observed with increasing prostate-specific antigen (PSA), GGG and T-stage, with comparable PSM rates across surgical modalities. Lymph node dissection was performed more commonly in high-risk cases (cT3, PSA > 20, GGG ⩾ 4). Pathological upstaging was common. Median length of stay was 1, 2 and 3 days for RARP, LRP and ORP, respectively. ORP had Clavien–Dindo complications ⩾3 and unplanned hospital readmissions. Conclusion: This analysis has enabled the first set of UK national RP standards to be produced allowing procedure, patient and disease-specific national, centre and individual comparisons. The present degree of service centralisation, operative modalities, and specific aspects of surgical practice can be observed. Level of evidence: 2b

Publisher

SAGE Publications

Subject

Urology,Surgery

Reference31 articles.

1. BAUS. Radical prostatectomy outcomes data. BAUS, https://www.baus.org.uk/patients/surgical_outcomes/radical_prostatectomy/default.aspx (2019, accessed 5 September 2019).

2. HQIP. Clinical outcomes publication: Technical manual. HQIP, 2016, https://www.hqip.org.uk/wp-content/uploads/2018/02/clinical-outcomes-publication-technical-manual.pdf

3. BAUS. BAUS surgical outcomes audit. BAUS, https://www.baus.org.uk/patients/surgical_outcomes/radical_prostatectomy/hospital.aspx?id=143 (2019, accessed 16 May 2019).

4. BAUS. Surgical outcomes audit webpage. BAUS, https://www.baus.org.uk/patients/surgical_outcomes/ (2019, accessed 4 September 2019).

5. The British Association of Urological Surgeons (BAUS) radical prostatectomy audit 2014/2015 - an update on current practice and outcomes by centre and surgeon case-volume

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