1. Laboratory of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Pontificia Universidad Católica de Chile, School of Medicine, and Department of Gastroenterology, Pontificia Universidad Católica de Chile, School of Medicine, Santiago, Chile; ICSM Maternal and Fetal Disease Group, MRC Clinical Sciences Center, Imperial College School of Medicine, Hammersmith Hospital, London, United Kingdom