What Have We Learnt from Bacterial Stool Culture Results? a Retrospective Study of Hospitalised Gastroenteritis Cases in a Regional Hospital in Hong Kong

Abstract

Background Stool culture is one of the common investigations done for patients with gastroenteritis, and fluoroquinolones have been used frequently for suspected bacterial gastroenteritis. Objective To study the yield of bacterial pathogens in stool culture in a local regional hospital for in-patients with gastroenteritis and the individual pathogens identified. Also, the value of stool culture and the prescription of fluoroquinolones as empirical antibiotics were reviewed. Methods This was a retrospective study. All in-patients with the principal diagnosis of “gastroenteritis” in the year 2007 were reviewed. We excluded pregnant patients and patients under 18 years of age. Patients were divided into two age groups and data were analysed including demographics, clinical findings, admission time and culture results. Antibiotics prescription behaviour was also analysed. Results A total of 837 adult patients fulfilled the criteria. Among them, 562 cases had their stool saved and sent for bacterial culture. Eighty-nine cases were found to have their stool cultures positive for bacteria. The identified pathogens were namely Vibrio parahaemolyticus (38.2%), Salmonella species (34.8%), Campylobacter species (11.2%), Plesiomonas species (10.1%) and Aeromonas species (3.4%) respectively. The yield of positive stool culture was 15.8%. Conclusion Vibrio parahaemolyticus and Salmonella species were still the most common pathogens for bacterial gastroenteritis among hospitalized patients in Hong Kong, especially in the young and middle aged. Their occurrence followed a seasonal pattern. Physicians had a tendency to prescribe fluoroquinolones for cases with fever and travel history. Also, the problem of antibiotic resistance did exist. It is important for practitioners to follow local guidelines before ordering microbiological investigations on stool and prescribing empirical antibiotic treatment.