Thrombolytic Therapy: A Comprehensive Review of its Use in Clinical Medicine—Part I

Author:

Bell William R.1,Streiff Michael B.1

Affiliation:

1. From the Department of Medicine, Johns Hopkins School of Medicine, Baltimore, MD

Abstract

In the first part of this comprehensive review of thrombolytic therapy in clinical medicine, we begin with a brief history of fibrinolysis, followed by a review of the components of die endogenous fibrinolytic system and the currently available plasminogen activators. An in-depth examination of thrombolysis in treatment of acute myocardial infarction follows, Including recommendations for management based on available clinical trial data. New developments in thrombolytic therapy are also discussed.

Publisher

SAGE Publications

Subject

Critical Care and Intensive Care Medicine

Reference109 articles.

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2. Hunter J. Treatise on blood, inflammation, and gunshot wounds. London: G. Nicoll, 1794: 575

3. THE FIBRINOLYTIC ACTIVITY OF HEMOLYTIC STREPTOCOCCI

4. A PROTEOLYTIC ENZYME OF SERUM: CHARACTERIZATION, ACTIVATION, AND REACTION WITH INHIBITORS

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