A Reconnaissance Study of a Potential Emerging Mexican Mesothelioma Epidemic due to Fibrous Zeolite Exposure

Author:

Ilgren E.B.1,Ortega Breña Mariana2,Castro Larragoitia Javier3,Loustaunau Navarrete Gustavo4,Fuentes Breña Alvar2,Krauss Edgar2,Fehér Guillermina2

Affiliation:

1. Bryn Mawr, Pennsylvania, USA,

2. National University of Mexico, Mexico City, México

3. San Luis Potosí University, México

4. Cuernavaca, Morelos, México

Abstract

A mesothelioma cluster has been found in a remote part of central Mexico. The region is primarily agricultural with no clear source of industrial asbestos exposure. This investigation has revealed that the mesothelioma cluster was situated on an area heavily laden with zeolites. Fibrous erionite was not found. However, the geological conditions and mineralogical characteristics of the affected area very closely resemble those parts of Turkey where mesotheliomas are epidemic and those parts of the western United States where erionite was taken for biological testing. Those biological tests abundantly confirmed the extreme carcinogenicity of erionite for mesothelioma production. This preliminary study should prompt additional investigation to confirm definitively the cause of the elevated mesothelioma risk.

Publisher

SAGE Publications

Subject

Public Health, Environmental and Occupational Health

Reference114 articles.

1. Asbestos-related mesothelioma: Evidence for a threshold in animals and humans

2. Background incidence of mesothelioma: Animal and human evidence

3. Iarc : Erionite IARC monographs on the evaluation of the carcinogenic risk of chemicals to humans: Silica and Some Silicates 1987; 42:225-239.

4. Baris Y. , Grandjean P. : Prospective study of mesothelioma mortality in turkish villages with exposure to fibrous zeolite: J Nat Cancer Inst 2006;98:414-417.

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