Suppository treatment in ulcerative proctitis

Author:

Si Yingjie1,Shao LanJun2,Gao Shanqing3,Wen Hongzhu1ORCID

Affiliation:

1. Department of Gastroenterology, Longhua Hospital, Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China

2. Department of Internal Medicine, Qingpu District Traditional Chinese Medicine Hospital, Shanghai, China

3. Department of Internal Medicine, Fengxian District Traditional Chinese Medicine Hospital, Shanghai, China

Abstract

Ulcerative proctitis (UP) is a common form of ulcerative colitis (UC), the number of patients with UP is increasing. Suppository treatment containing mesalamine is usually the first-line choice for mild to moderate UP, here, we review the publications on mesalamine suppository in UP, to better understand its dosage, duration of therapy and adverse events in both induction and maintenance phases. We also review articles on budesonide, beclomethasone, tacrolimus, herbal medicine and acetarsol suppositories in UP, to present therapeutic strategies for patients with UP refractory to mesalamine suppository.

Funder

Research Project of Longhua Hospital in 2016

Scholar Project of Longhua hospital

National Natural Science Foundation of China

Publisher

SAGE Publications

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