1. Investigation performed at the Department of Orthopaedic Surgery, University Medical Center Freiburg, Freiburg, Germany
2. Department of Orthopaedic Surgery, University Medical Center Rostock, Rostock, Germany.
3. Department or Orthopaedic Surgery, University Medical Center Freiburg, Freiburg, Germany.
4. TransTissue Technologies GmbH, Berlin, Germany.
5. Address correspondence to Christian Kaps, PhD, Department of Rheumatology, Charitè Campus Mitte, Charitè – Universitätsmedizin Berlin, Charitè -platz 1, 10117 Berlin, Germany (e-mail: ). Drs Kreuz and Müller contributed equally to this work.
6. Department of Rheumatology, Charitè Campus Mitte, Charitè – Universitätsmedizin Berlin, Berlin, Germany.