Computational Radiology in Breast Cancer Screening and Diagnosis Using Artificial Intelligence

Author:

Tran William T.12ORCID,Sadeghi-Naini Ali13ORCID,Lu Fang-I4,Gandhi Sonal56,Meti Nicholas5,Brackstone Muriel7,Rakovitch Eileen12,Curpen Belinda89

Affiliation:

1. Department of Radiation Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada

2. Department of Radiation Oncology, University of Toronto, Toronto, Canada

3. Department of Electrical Engineering and Computer Science, Lassonde School of Engineering, York University, Toronto, Canada

4. Department of Laboratory Medicine and Molecular Diagnostics, Sunnybrook Health Sciences Centre, Toronto, Canada

5. Division of Medical Oncology, Sunnybrook Health Sciences Centre, Toronto, Canada

6. Department of Medicine, University of Toronto, Toronto, Canada

7. Department of Surgical Oncology, London Health Sciences Centre, London, Ontario

8. Division of Breast Imaging, Sunnybrook Health Sciences Centre, Toronto, Canada

9. Department of Medical Imaging, University of Toronto, Toronto, Canada

Abstract

Breast cancer screening has been shown to significantly reduce mortality in women. The increased utilization of screening examinations has led to growing demands for rapid and accurate diagnostic reporting. In modern breast imaging centers, full-field digital mammography (FFDM) has replaced traditional analog mammography, and this has opened new opportunities for developing computational frameworks to automate detection and diagnosis. Artificial intelligence (AI), and its subdomain of deep learning, is showing promising results and improvements on diagnostic accuracy, compared to previous computer-based methods, known as computer-aided detection and diagnosis. In this commentary, we review the current status of computational radiology, with a focus on deep neural networks used in breast cancer screening and diagnosis. Recent studies are developing a new generation of computer-aided detection and diagnosis systems, as well as leveraging AI-driven tools to efficiently interpret digital mammograms, and breast tomosynthesis imaging. The use of AI in computational radiology necessitates transparency and rigorous testing. However, the overall impact of AI to radiology workflows will potentially yield more efficient and standardized processes as well as improve the level of care to patients with high diagnostic accuracy.

Funder

Canadian Institutes of Health Research

Natural Sciences and Engineering Research Council of Canada

Terry Fox Research Institute

Publisher

SAGE Publications

Subject

Radiology Nuclear Medicine and imaging,General Medicine

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