Cardiac Imaging in Myocarditis: Current Evidence and Future Directions

Author:

Urzua Fresno Camila1,Sanchez Tijmes Felipe12,Shaw Kirsten E.3ORCID,Huang Flora4,Thavendiranathan Paaladinesh145,Khullar Sharmila6,Seidman Michael A.67,Hanneman Kate15ORCID

Affiliation:

1. Department of Medical Imaging, Toronto General Hospital, Peter Munk Cardiac Center, University Health Network (UHN), University of Toronto, Toronto, ON, Canada

2. Department of Medical Imaging, Clinica Santa Maria, Universidad de los Andes, Santiago, Chile

3. Department of Cardiology, Hennepin Healthcare/Minneapolis Heart Institute, Minneapolis, MN, USA

4. Division of Cardiology, Peter Munk Cardiac Centre, Toronto General Hospital, University Health Network, Toronto, ON, Canada

5. Toronto General Hospital Research Institute, University Health Network (UHN), University of Toronto, Toronto, ON, Canada

6. Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada

7. Laboratory Medicine Program, University Health Network, Toronto, ON, Canada

Abstract

Myocarditis is defined as a non-ischemic inflammatory disease of the myocardium. It remains a challenge to diagnose given non-specific symptoms and lack of specific blood biomarkers. Cardiac imaging plays an important role in the evaluation of myocarditis with unique strengths and limitations of different imaging modalities, including cardiac magnetic resonance imaging, echocardiography, cardiac computed tomography, and positron emission tomography. The purpose of this review is to discuss the strengths and limitations of various cardiac imaging techniques in the evaluation of myocarditis, review imaging findings in specific causes of myocarditis including COVID-19 and after vaccination, evaluate the role of imaging in differentiating myocarditis from potential mimics and differential considerations, identify current gaps in knowledge, and propose future directions.

Publisher

SAGE Publications

Subject

Radiology, Nuclear Medicine and imaging,General Medicine

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