A Patient with Intractable Posthypoxic Myoclonus (Lance-Adams Syndrome) Treated with Sodium Oxybate

Author:

Arpesella R.1,Dallocchio C.12,Arbasino C.12,Imberti R.13,Martinotti R.1,Frucht S. J.14

Affiliation:

1. Department of Intensive Care and Emergency Unit, Ospedale Civile, Voghera, Italy

2. Division of Neurology, Ospedale Civile.

3. 2nd Department of Anaesthesiology and Critical Care Medicine, Fondazione IRCCS Policlinico S. Matteo, Pavia.

4. Department of Neurology, Columbia University Medical Center, New York, United States of America.

Abstract

Posthypoxic myoclonus is a rare and devastating complication of near-fatal cardiopulmonary arrest. Despite treatment with available anti-myoclonic agents, some patients may recover cognitively but remain completely disabled by severe myoclonus. We report a 16-year-old patient with severe treatment-refractory posthypoxic myoclonus, which improved markedly with administration of the drug sodium oxybate.

Publisher

SAGE Publications

Subject

Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine

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1. Myoclonus;Movement Disorders Phenomenology;2024

2. Post-hypoxic myoclonus; what we know and gaps in knowledge;Tropical Doctor;2023-06-07

3. Lance-Adams syndrome: An unusual complication of snakebite envenomation;Toxicon;2022-04

4. Posthypoxic Myoclonus and Its Management;Movement Disorder Emergencies;2021-10-03

5. Sodium-oxybate;Reactions Weekly;2021-05

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