Affiliation:
1. Department of Intensive Care, Sir Charles Gairdner Hospital, Perth, Western Australia
Abstract
Nitric oxide 10 ppm and inhaled aerosolized prostacyclin 50 ng/kg/min were compared as selective pulmonary vasodilators in five patients with hypoxaemia secondary to acute respiratory distress syndrome. Neither agent resulted in systemic haemodynamic changes, indicating true pulmonary selectivity. Inhaled aerolized prostacyclin improved oxygenation to a degree comparable to nitric oxide, as measured by the arterial alveolar oxygen partial pressure gradient and shunt fraction.
Subject
Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine
Cited by
49 articles.
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