Sedation for Vitreoretinal Surgery: A Comparison of Anaesthetist-Administered Midazolam and Patient-Controlled Sedation with Propofol

Author:

Morley H. R.12,Karagiannis A.1,Schultz D. J.1,Walker J. C.1,Newland H. S.13

Affiliation:

1. Department of Anaesthesia and Intensive Care and Department of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia

2. Department of Anaesthesia and Intensive Care.

3. Department of Ophthalmology.

Abstract

Local anaesthesia is increasingly being used for vitreoretinal surgery, but the optimal technique for sedation remains unclear. Anaesthetist-administered midazolam, which is often used, was compared in this study to patient-controlled sedation with propofol in 43 patients undergoing 50 vitreoretinal procedures. A variety of patient, anaesthetist and surgical endpoints were measured. There were no significant outcome differences between the two agents except that midazolam produced more amnesia for the local anaesthetic eye block. However, several outcomes and the observations in patients who experienced both agents showed a trend in favour of propofol for intraoperative sedation. We conclude that both approaches are safe and that patient-controlled sedation with propofol is at least as satisfactory as anaesthetist-administered midazolam.

Publisher

SAGE Publications

Subject

Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine

Cited by 17 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Anesthesia Techniques for Vitreoretinal Surgery in the United States: A Report from the Multicenter Perioperative Outcomes Group Research Consortium;American Journal of Ophthalmology;2024-11

2. Vitreoretinal Anesthesia;Practical Manual of Vitreoretinal Surgery;2024

3. Effectiveness and safety of intravenous dexmedetomidine sedation for ophthalmic surgery under regional anesthesia;European Journal of Ophthalmology;2021-11-12

4. Sedation during vitreoretinal surgery: practice patterns in Canada;Canadian Journal of Anesthesia/Journal canadien d'anesthésie;2020-05-04

5. Propofol;Meyler's Side Effects of Drugs;2016

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