Paraganglioma in pregnancy: A case series and literature review

Author:

Eccles-Smith Jade1ORCID,Hopkins Stephanie2,Conn Jennifer134,Johnston Stephanie56,Szabo Rebecca178ORCID,Price Sarah134,Nankervis Alison134

Affiliation:

1. Department of Obstetrics and Gynaecology, Royal Women’s Hospital, Parkville Victoria, Australia

2. Department of Medicine, University of Newcastle, Callaghan New South Wales, Australia

3. Department of Diabetes and Endocrinology, Royal Melbourne Hospital, Australia

4. Department of Medicine, University of Melbourne, Parkville Victoria, Australia

5. University Hospital, Geelong Victoria, Australia

6. School of Medicine, Deakin University, Geelong Victoria, Australia

7. Department of Medical Education, University of Melbourne, Parkville Victoria, Australia

8. Gandel Simulation Service, Royal Women’s Hospital, University of Melbourne, Parkville Victoria, Australia

Abstract

Paragangliomas are rare neuroendocrine neoplasms which are often catecholamine-secreting and associated with familial syndromes. Described here are three women with a variety of pathology: isolated secretory paraganglioma diagnosed in pregnancy, secretory metastatic paraganglioma in pregnancy and non-secretory metastatic paraganglioma in pregnancy. Whilst paragangliomas are associated with morbidity and mortality during pregnancy, good maternal and fetal outcomes can be achieved through individualised care within the context of a multidisciplinary team. Although paragangliomas are associated with morbidity and mortality in pregnancy, good maternal and fetal outcomes can be achieved through individualised care within the context of a multidisciplinary team.

Publisher

SAGE Publications

Subject

Obstetrics and Gynecology

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