Diagnosis, management and outcomes of primary hypokalemic periodic paralysis during pregnancy

Author:

Jha Nivedita1ORCID,Balachandran Divya Mecheril1,Thabah Molly Mary2,Jha Ajay Kumar3ORCID

Affiliation:

1. Department of Obstetrics and Gynaecology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India

2. Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India

3. Department of Anaesthesiology and Critical Care, Jawaharlal Institute of Medical Education and Research, Pondicherry, India

Abstract

Primary hypokalaemic periodic paralysis during pregnancy has been rarely reported. Four pregnant women with the acute onset of flaccid paralysis presented between January 2018 and December 2021. Focussed history and physical examination helped an appropriate radiological and laboratory investigation plan to be made. All women recovered within 4–7 days of potassium supplementation. Supplemental potassium continued until delivery. A pain management plan with continuous epidural infusion helped in avoiding stress-induced hypokalaemia. None of the women developed an episode of muscle weakness during the intervening period. In conclusion, a focussed history and targeted laboratory investigation are needed to diagnose primary hypokalaemic periodic paralysis. Early administration of oral or intravenous potassium is crucial in improving fetomaternal outcomes.

Publisher

SAGE Publications

Subject

Obstetrics and Gynecology

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