Two case reports of generalized pustular psoriasis of pregnancy: Different outcomes

Author:

Flynn Aoibheann1,Burke Naomi2,Byrne Bridgette3,Gleeson Noreen2,Wynne Bairbre1,Barnes Louise1

Affiliation:

1. Department of Dermatology, St. James’s Hospital Dublin, Dublin, Ireland

2. Department of Gynaecology, St. James’s Hospital Dublin, Dublin, Ireland

3. Department of Obstetrics and Gynaecology, The Coombe Women and Infants Maternity Hospital, Dublin, Ireland

Abstract

Generalized pustular psoriasis of pregnancy is a rare dermatosis with potential serious consequences for both the mother and fetus. Treatment is difficult and historically steroids were the mainstay of treatment. Cyclosporin has been used for a few cases resistant to steroids. We report our own experience of two cases of generalized pustular psoriasis of pregnancy. Cases of generalized pustular psoriasis of pregnancy need review by a dermatologist with experience of skin disorders in pregnancy. Both the fetus and mother need to be monitored closely when systemic illness occurs, as there is a risk of stillbirth. Maternal sepsis is a known complication of generalized pustular psoriasis of pregnancy. Cyclosporin, when used appropriately is effective and relatively safe.

Publisher

SAGE Publications

Subject

Obstetrics and Gynecology

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