National survey of safe handling of hazardous drugs in hospital settings: Use of an innovative approach

Author:

Pinet Emma1,Langlais Annie2,Chouinard Audrey34,Bussières Jean-François15,Tanguay Cynthia1ORCID

Affiliation:

1. Unité de recherche en pratique pharmaceutique, Pharmacy Department, CHU Sainte-Justine, Montréal, Québec, Canada

2. Pharmacy Department, CHu de Québec - Université Laval (Québec), Québec, Canada

3. Nursing Department, Centre hospitalier de l'Université de Montréal, Montréal, Québec, Canada

4. Faculté des sciences infirmières, Université de Montréal, Montréal, Québec, Canada

5. Faculté de pharmacie, Université de Montréal, Montréal, Québec, Canada

Abstract

Introduction Workers can reduce their risk of exposure to hazardous drugs by following safe handling guidelines. Healthcare centers need to dedicate time and resources in order to implement new safety recommendations. The objective was to present the results of a national survey about the safe handling of hazardous drugs in healthcare centers. Methods Quebec healthcare centers performed an auto-evaluation to the newly updated safe handling guidelines in 2021. Centers rated each criterion as compliant or non-compliant. The guidelines tailored recommendations according to three categories of hazards: G1, consisting mostly of carcinogenic drugs; G2, other hazardous drugs; and G3, those with reproductive toxicity. The questionnaire prompted participants to document their planned corrective measures for non-compliant criteria. Results Most centers participated (28/29, 97%). The overall compliance was 58% (8761/15,216 criteria). The conformity per theme was hygiene and sanitation (1290/1,878, 69%), laundry (221/367, 60%), pharmacy (2658/4,474, 59%), nursing (3436/6,017, 57%), spills and accidental exposure (353/649, 54%), and general measures (803/1,831, 44%). It was higher for recommendations regarding G1s (4226/6,115, 69%) than for G2s (1626/3557, 46%) and G3s (372/916, 41%). Conclusions This project successfully used an innovative approach that combined a national auto-evaluation survey, an actionable report, and the involvement of a community of practice. Centers were able to benchmark their implementation of safe handling guidelines, and community of practices may help in sharing the best practices. The design of the questionnaire helped in targeting corrective measures. More work is needed for safe handling practices that relate to G2 and G3 drugs.

Publisher

SAGE Publications

Subject

Pharmacology (medical),Oncology

Reference25 articles.

1. National Institute for Occupational Safety and Health. NIOSH list of hazardous drugs in healthcare settings 2020. Publication Number 2020-xxx (Supersedes 2016-161), https://www.cdc.gov/niosh/docket/review/docket233c/pdfs/DRAFT-NIOSH-Hazardous-Drugs-List-2020.pdf. 2020.

2. Exposure to Antineoplastic Drugs in Occupational Settings: A Systematic Review of Biological Monitoring Data

3. Canadian monitoring program of the surface contamination with 11 antineoplastic drugs in 124 centers

4. Occupational Exposure Assessment to Antineoplastic Drugs in Nine Italian Hospital Centers over a 5-Year Survey Program

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