Oral anticancer medicine interventions: A cross-sectional study in French community pharmacies

Author:

Macé Florent1ORCID,Peyron Christine1,Cransac Amélie2ORCID,Pistre Pauline2ORCID,Boulin Mathieu3

Affiliation:

1. Economics Laboratory of Dijon (LEDi), EA 7467, University of Burgundy & Franche Comte, Dijon, France

2. Department of Pharmacy, University Hospital and LNC UMR 1231, University of Burgundy& Franche Comte, Dijon, France

3. Department of Pharmacy, University Hospital and EPICAD LNC UMR 1231, University of Burgundy & Franche Comte, Dijon, France

Abstract

Introduction The increasing number of oral anticancer medicines (OAMs) dispensed in community pharmacies and the associated challenges (misuse, management of side effects) give the community pharmacist (CP) a major role in the pharmacotherapeutic management of cancer patients. In France, as a response to these challenges, cancer outpatients can schedule a meeting with their CP to ensure the safe and effective use of OAMs. The objectives of this study were to evaluate the perspectives of these interventions regarding their implementation and the opinion of French CPs. Methods A declarative survey and semi-structured interviews were conducted with CPs that dispensed at least one OAM between January 2021 and March 2022. The study was conducted between April and August 2022. Results Eighty-five CPs completed the survey. Of these pharmacists, 21% ( n = 18) had already performed OAM interventions and 91% ( n = 61) wanted to implement them. Lack of time, knowledge and training were the main barriers to implementation. No correlations were identified between the characteristics of community pharmacies and the likelihood of implementing OAM interventions. Conclusions Considering that CPs seem willing to implement them and the favourable context in France, this observational study highlights the potential of OAM interventions to improve the management of cancer patients. Though further studies are required to better evaluate the implementation and the potential effects of these interventions, OAM interventions could be relevant strategies in other healthcare systems to secure the management of cancer patients through the involvement of the CP.

Funder

Agence Nationale de la Recherche

Conseil Régional de Bourgogne-Franche-Comté

Publisher

SAGE Publications

Reference33 articles.

1. Cancer Research UK. Worldwide cancer statistics, https://www.cancerresearchuk.org/health-professional/cancer-statistics/worldwide-cancer (accessed 10 November 2023).

2. Do people with cancer comply with oral chemotherapy treatments?

3. Pharmaceutical Group of European Union. PGEU Position Paper on Cancer, https://www.pgeu.eu/wp-content/uploads/2020/12/The-Community-Pharmacy-Contribution-to-Europe-s-Beating-Cancer-Plan-Web.pdf (2020).

4. Parcours de soins : modélisation et analyse des risques induits par les anticancéreux oraux

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