Familial Mediterranean fever: a differential diagnosis for the surgical abdomen

Author:

Cliff-Patel Nikita1,Yusuf Baasil Syed23ORCID,Hamdani Shazia1,Ziauddin Veqas1

Affiliation:

1. East Surrey Hospital, Redhill, UK

2. Royal London Hospital, London, UK

3. Barts and The London School of Medicine and Dentistry, London, England

Abstract

FMF is characterised by dysregulation of the inflammatory process in the body, presenting as recurrent episodes of serositis. Patients with FMF commonly present with episodes of fever, peritonitis, synovitis, pleuritis, arthritis, and occasionally pericarditis. We present a case of a young 19-year old female, who presented to hospital four times over several months with intermittent fevers, abdominal pain and pleuritic chest pain. After being initially admitted under the surgical team, she was reviewed by the medical team who referred her for genetic testing, which subsequently confirmed the diagnosis. She was started on colchicine, and her symptoms remain well controlled one-year post diagnosis.

Publisher

SAGE Publications

Subject

General Medicine

Reference14 articles.

1. Diagnosis and management of familial Mediterranean fever: Integrating medical genetics in a dedicated interdisciplinary clinic

2. Relationship between clinical findings and genetic mutations in patients with familial Mediterranean fever

3. Frequency of Abdominal Surgery in Patients with Familial Mediterranean Fever

4. NHS England. Clinical commissioning policy: Canakinumab for treating periodic fever syndromes: TRAPS, HIV/MKD and FMF (ages 2 years and older). Available from: https://www.england.nhs.uk/wp-content/uploads/2020/03/Canakinumab-for-treating-periodic-fever-syndromes-TRAPS-HIDSMKD-and-FMF-ages-2-years-and-older.pdf

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