Endothelial follistatin‐like‐1 regulates the postnatal development of the pulmonary vasculature by modulating BMP/Smad signaling

Author:

Tania Navessa P.1,Maarsingh Harm2,T. Bos I. Sophie1,Mattiotti Andrea3,Prakash Stuti3,Timens Wim4,Gunst Quinn D.3,Jimenez‐Borreguero Luis J.5,Schmidt Martina1,Hoff Maurice J.B.3,Gosens Reinoud1

Affiliation:

1. University of GroningenDepartment of Molecular PharmacologyGroningen Research Institute for Asthma and COPDGroningenThe Netherlands

2. Palm Beach Atlantic UniversityDepartment of Pharmaceutical SciencesLloyd L. Gregory School of PharmacyWest Palm BeachFLUSA

3. Academic Medical CenterDepartment of AnatomyEmbryology and PhysiologyAmsterdamThe Netherlands

4. University of GroningenUniversity Medical Center GroningenDepartment of Pathology and Medical BiologyGroningen Research Institute for Asthma and COPDGroningenThe Netherlands

5. Centro Nacional de Investigaciones Cardiovasculares & Hospital de La PrincesaMadridSpain

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Reference49 articles.

1. BMP signaling in vascular development and disease;Lowery JW;Cytokine Growth Factor Rev,2010

2. Dosage‐dependent requirement of BMP type II receptor for maintenance of vascular integrity;Liu D;Blood,2007

3. Mutations of the TGF‐beta type II receptor BMPR2 in pulmonary arterial hypertension;Machado RD;Hum Mutat,2006

4. Molecular and functional analysis identifies ALK‐1 as the predominant cause of pulmonary hypertension related to hereditary haemorrhagic telangiectasia;Harrison RE;J Med Genet,2003

5. Implications of mutations of activin receptor‐like kinase 1 gene (ALK1) in addition to bone morphogenetic protein receptor II gene (BMPR2) in children with pulmonary arterial hypertension;Fujiwara M;Circ J Off J Jpn Circ Soc,2008

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