Selective improvement of pulmonary arterial hypertension with a dual ET A /ET B receptors antagonist in the apolipoprotein E −/− model of PAH and atherosclerosis

Author:

Renshall Lewis1,Arnold Nadine1,West Laura1,Braithwaite Adam1,Pickworth Josephine1ORCID,Walker Rachel2,Alfaidi Mabruka1,Chamberlain Janet1,Casbolt Helen1,Thompson A.A. Roger1ORCID,Holt Cathy2,Iglarz Marc3,Francis Sheila1,Lawrie Allan1ORCID

Affiliation:

1. Department of InfectionImmunity and Cardiovascular ScienceUniversity of SheffieldSheffieldUK

2. Institute for Cardiovascular ScienceUniversity of ManchesterManchesterUK

3. Actelion Pharmaceuticals Ltd.AllschwilSwitzerland

Funder

British Heart Foundation

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Reference47 articles.

1. Survival in patients with primary pulmonary hypertension;D’Alonzo GE;Ann Intern Med,1991

2. Elderly patients diagnosed with idiopathic pulmonary arterial hypertension: results from the COMPERA registry;Hoeper MM;Int J Cardiol,2013

3. Institute of Medicine (US) Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries Fuster V Kelly BB (eds)Epidemiology of Cardiovascular Disease. Washington DC: National Academies Press (US) 2010.

4. Cardiovascular disease in the developing world: prevalences, patterns, and the potential of early disease detection;Celermajer DS;J Am Coll Cardiol,2012

5. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report;National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III);Circulation,2002

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