Lipid Status During Combined Treatment in Prostate Cancer Patients

Author:

Wolny-Rokicka Edyta12ORCID,Tukiendorf Andrzej3,Wydmański Jerzy4,Ostrowska Małgorzata5,Zembroń-Łacny Agnieszka2

Affiliation:

1. Department of Radiotherapy, Multidisciplinary Hospital, Gorzow Wielkopolski, Poland

2. Faculty of Medicine and Health Sciences, University of Zielona Góra, Zielona Góra, Poland

3. Social Medicine Department, Medical University, Wrocław, Poland

4. Department of Radiotherapy, Centre of Oncology, Maria Skłodowska-Curie Memorial Institute, Branch in Gliwice, Poland

5. Department of Nephrology, Medical University Hospital of Karol Marcinkowski, Zielona Góra, Poland

Abstract

The aim of this study was to provide a specific review of current medical literature regarding the lipid profile during prostate carcinoma (PCa) treatment. The main aim was to analyze the results presented by different authors and to find a commonality in the changes occurring during the treatment—hormonotherapy. The levels of total cholesterol (TC), triglycerides (TG), high-density lipoprotein (HDL) cholesterol, and low-density lipoprotein (LDL) cholesterol were measured before and after the follow-up treatment. The manuscripts reviewed came from the period between 2008 and 2016. The size of the studies ranged from 16 participants to 310. The mean age was from 65 to 74 years in all studies. The Q test was used to attain all lipid parameters and to specify heterogeneity ( p < .0001). After 12 months of androgen deprivation therapy (ADT), the patients had a significantly higher level serum TC and TG.

Publisher

SAGE Publications

Subject

Public Health, Environmental and Occupational Health,Health (social science)

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