Bone Mineral Density Reference Values in 18- to 95-Year-Old Population in Lombardy Region, Italy

Author:

Rondanelli Mariangela12,Gasparri Clara3ORCID,Perdoni Federica3,Riva Antonella4,Petrangolini Giovanna4,Peroni Gabriella3,Faliva Milena Anna3,Naso Maurizio3,Perna Simone5

Affiliation:

1. IRCCS Mondino Foundation, Pavia, Italy

2. Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Pavia, Italy

3. Endocrinology and Nutrition Unit, Azienda di Servizi alla Persona “Istituto Santa Margherita,” University of Pavia, Pavia, Italy

4. Research and Development Unit, Indena, Milan, Italy

5. Department of Biology, College of Science, University of Bahrain, Zallaq, Kingdom of Bahrain

Abstract

The aim of this study is to assess the bone mineral density (BMD) and T-score reference values in a population from 18 to 95 years old in Lombardy region, Italy. This study also investigates the association between BMD values and body mass index (BMI) divided by gender and age. The evaluation of BMD was analyzed by T-score and BMD in each site, femur, and column. A total of 10,503 patients (9,627 females and 876 males, 65.04±12.18 years) have been enrolled in this study. The women hip femur reference values associated with a situation of osteopenia highlighted in-line with the class of age of 45 to 55 years were: mean values: −1.3132 T-score; 95% confidence interval (CI): −1.3600 to −1.2664 and of osteoporosis from the class of age 85 to 95 years, mean values: −2.6591 T-score, 95% CI: −2.7703 to −2.5479. The men hip femur reference values associated with a situation of osteopenia highlighted in-line with the class of age of 45 to 55 years were: mean values: 1.2986 T-score; 95% CI: −1.5454 to −1.0518. A positive association between BMI and the two sites of BMD was recorded ( p > .05). This study provides an Italian overview of national and regional reference values about the BMD and T-score values divided by age and gender as reference values for clinicians for a correct assessment and monitoring.

Publisher

SAGE Publications

Subject

Public Health, Environmental and Occupational Health,Health (social science)

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