Affiliation:
1. Preclinical toxicity tests in dogs cannot be used to predict that a new drug will not have unacceptable adverse effects in humans, so they should not be a regulatory requirement
Subject
Medical Laboratory Technology,Toxicology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference8 articles.
1. Anon. (1986). Animals (Scientific Procedures) Act 1986, 36 pp. London, UK: HMSO.
2. The ability of animal studies to detect serious post marketing adverse events is limited
3. BroadheadC.L., JenningsM. & CombesR. (1999). A Critical Evaluation of the Use of Drugs in the Regulatory Testing of Pharmaceuticals, 106 pp. Nottingham, UK: FRAME.
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2 articles.
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