Alternatives to Animal Testing in the Quality Control of Immunobiologicals: Current Status and Future Prospects

Author:

Hendriksen Coenraad F.M.1,Garthoff Bernward2,Aggerbeck Henrik3,Bruckner Lucas4,Castle Peter5,Cussler Klaus6,Dobbelaer Roland7,van de Donk Huib1,van der Gun Johan1,Lefrancois Sylvie8,Milstien Julie9,Minor Philip D.10,Mougeot Hubert11,Rombaut Bart12,Ronneberger Hansjorg D.13,Spieser Jean-Marc5,Stolp Ruurd14,Straughan Donald W.15,Tollis Maria16,Zigtermans Gy17

Affiliation:

1. National Institute of Public Health and Environmental Protection (RIVM), P.O. Box 1, 3720 BA Bilthoven, The Netherlands

2. Bayer AG, PF-Zentrum Mannheim, D-51368 Leverkusen, Germany

3. Bacterial Vaccine Department, Statens Seruminstitut, Artillerivej 5, DK-2300 Copenhagen S, Denmark

4. Institute of Virology and Immunoprophylaxis, P.O. Box 3147, Mittelhausern, Switzerland

5. European Pharmacopoeia Commission, B.P. 907, F-67029 Strasbourg Cedex 1, France

6. Paul Ehrlich Institut, P.O. Box 1740, D-63207 Langen, Germany

7. Afd. Biologische Standaardisatie, Ministerie van Hygiene en Epidemiologic, Juliette Wytmanstraat 14, B-1050 Brussels, Belgium

8. Coordination Vaccins, Agence du Medicament, Direction des Laboratoires et des Controles, Unité Pharmacologie-Toxicologie, 14 rue École de Pharmacie, 3400 Montpellier, France

9. WorldHealth Organisation—Biologicals, CH-1211 Geneva 27, Switzerland

10. Division of Virology, National Institute for Biological Standards and Control (NIBSC), Blanche Lane, South Mimms, Potters Bar, Hertfordshire EN6 3QG, UK

11. Rhone Merieux, Laboratoire IFFA, 254 rue Marcel Merieux, BP 7009, F-69007 Lyon, France

12. Galenica, Microbiology and Hygiene, Vrije Universiteit Brussel, Laarbeeklaan 103, B-1090 Brussels, Belgium

13. Behringwerke AG, Biological Research, P.O. Box 1140, D-35001 Marburg an der Lahn, Germany

14. lntervet Inc., 405 State Street, P.O. Box 318, Millsboro, DE 19966, USA

15. FRAME, Russell & Burch House, 96–98 North Sherwood Street, Nottingham NG1 4EE, UK

16. Istituto Superiore di Sanità, Laboratorio di Medecina Veterinaria, Viale Regina Elena 299, I-00161 Rome, Italy

17. Intervet International B.V., W. de Korvestraat 35, 5831 AN Boxmeer, The Netherlands.

Publisher

SAGE Publications

Subject

Medical Laboratory Technology,Toxicology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference3 articles.

1. Anon. (1993). Statistics of Scientific Procedures on Living Animals in Great Britain 1992, 49 pp. London: HMSO.

2. Anon. (1993). Animal Experimentation in the Netherlands, 27 pp. Rijswijk, The Netherlands: Veterinary Public Health Inspectorate.

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