Affiliation:
1. Laboratorio di Biocompatibilità dei Materiali da Impianto, Istituto Ortopedico Rizzoli, via di Barbiano 1/10, 40136 Bologna, Italy
Abstract
Cell culture techniques are usually used in the field of biomaterials research and development in order to detect toxic components. Morphological assays are the most widely used methods and give the very first information about the biological compatibility of materials. Cell function assays give more quantitative data, but the comparison of data between different laboratories is difficult. Some of the cell culture methods that are used for biocompatibility studies are described briefly here, and results from our laboratory are reported. Despite some inherent limitations of the cell culture techniques, they are an accurate and reliable method of predicting the biological compatibility of materials to be implanted in vivo.
Subject
Medical Laboratory Technology,Toxicology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference13 articles.
1. WilliamsD.F. ed (1987). Definitions in Biomaterials. Proceedings of a Consensus Conference of the European Society for Biomaterials, Chester, England, 3–5, March 1986, Progress in Biomedical Engineering, 4, pp. 1–72. Oxford: Elsevier.
2. Agar Diffusion Method for Toxicity Screening of Plastics on Cultured Cell Monolayers
3. Tissue Culture Method for Screening Toxicity of Plastic Materials to be Used in Medical Practice
4. In vitro and in vivo interactions of cells with biomaterials
Cited by
4 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献