Ewing's Sarcoma and Peripheral Primitive Neuroectodermal Tumor: An Interim Report

Author:

Batsakis John G.1,MacKay Bruce1,El-Naggar Adel K.1

Affiliation:

1. Houston, Texas

Abstract

The primitive neuroectoderm and its progeny seemingly give rise to an ever-increasing number of clinicopathologic entities. Ewing's sarcoma and peripheral primitive neuroectodermal tumor have recently been united by relatively unique antigens expressed by the MIC-2 gene, commonly coexpressed neural markers, and cytogenetic and molecular genetic abnormalities. Because of these factors, the current thinking is that Ewing's sarcoma and the peripheral primitive neuroectodermal tumor are parts of a phenotypic spectrum. We present an “interim report” on this group of neoplasms, emphasizing their presentation in the head and neck

Publisher

SAGE Publications

Subject

General Medicine,Otorhinolaryngology

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