Steroid Administration Approach for Idiopathic Sudden Sensorineural Hearing Loss: A National Survey in China

Author:

Yao Qingxiu123ORCID,Jiang Zhuang123,Zhang Jiajia123,Huang Shujian123,He Shouhuan4,Feng Yanmei123,Wang Hui123ORCID,Yin Shankai123

Affiliation:

1. Department of Otolaryngology-Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, China

2. Otolaryngology Institute of Shanghai Jiao Tong University, Shanghai, China

3. Shanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, China

4. Department of Otolaryngology, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai, China

Abstract

Objective: To optimize a protocol for the steroid administration approach for idiopathic sudden sensorineural hearing loss (ISSNHL) in China. Methods: A questionnaire was distributed to otolaryngologists. The data on demographics, indications for first-line and salvage treatment, such as intratympanic administration of steroids (ITS) and postauricular steroids (PAS), and procedures were analyzed. Results: 74 respondents used oral steroids, 112 used intravenous injections, 10 used ITS and 6 used PAS as a monotherapy for first-line treatment, and 135 used ITS or PAS in conjunction with oral or intravenous injection as a first-line treatment. Of the 249 respondents who used ITS, 97.19% adopted it as salvage therapy. The most commonly used steroid was 0.5 ml dexamethasone at 5 mg/ml and the most common side effect was pain. Of the 174 respondents who used PAS, 94.25% used it as salvage therapy. The most commonly used steroid was 0.5 ml methylprednisolone mixed with 0.5 ml lidocaine. Conclusions: The obtained data suggested that intravenous injection of steroids was the most popular treatment for ISSNHL and that ITS or PAS were used as a salvage treatment in China.

Funder

the Funds for International Cooperation and Exchange of the National Natural Science Foundation of China

Clinical Research of the Three-year Plan Fund of Shanghai Shenkang Development Center

National Natural Science Foundation of China

the State Key Program of National Natural Science of China

Publisher

SAGE Publications

Subject

General Medicine,Otorhinolaryngology

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