Amyloidosis of the Larynx in a Child

Author:

O'Halloran Laurence R.1,Lusk Rodney P.1

Affiliation:

1. St Louis, Missouri

Abstract

Localized laryngeal amyloidosis is a rare and benign process. Only three cases have been reported in children. We present the case of a 9-year-old girl with localized laryngeal amyloidosis that was excised via laryngofissure. The patient presented with a 3- to 4-week history of progressive hoarseness. Direct laryngoscopy revealed a smooth, firm, submucosal mass extending from the anterior aspect of the left false vocal cord to the vocal process. Biopsy of the mass revealed findings consistent with amyloidosis. The mass was approached via laryngofissure and excised with the thyroid cartilage and left true vocal cord left intact. An extensive workup for systemic amyloidosis was negative, including bone marrow biopsy. The postoperative recovery was uneventful, with good vocal quality and a sluggish but mobile left true vocal cord. This case is significant because of the young age of the child, the extent of disease, and the use of laryngofissure for excision.

Publisher

SAGE Publications

Subject

General Medicine,Otorhinolaryngology

Cited by 24 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Localized laryngeal amyloidosis: A systematic review;American Journal of Otolaryngology;2022-09

2. Laryngeal amyloidosis;Otorinolaringologia;2020-04

3. Sleep disordered breathing and dysphonia in a pediatric patient – Laryngeal amyloidosis as an unusual diagnosis;International Journal of Pediatric Otorhinolaryngology;2019-07

4. A case report of amyloidosis of the larynx in a 13-year-old girl;Vestnik otorinolaringologii;2019

5. Laryngeal amyloidosis: diagnosis, pathophysiology and management;The Journal of Laryngology & Otology;2017-05-30

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