Isolated medial longitudinal fasciculus syndrome: Review of imaging, anatomy, pathophysiology and differential diagnosis

Author:

Kochar Puneet S1,Kumar Yogesh1,Sharma Pranav1,Kumar Vikash2,Gupta Nishant3,Goyal Pradeep3

Affiliation:

1. Department of Radiology, Yale New Haven Health Bridgeport Hospital, USA

2. Department of Radiology, BLK Superspeciality Hospital, India

3. Department of Radiology, St. Vincent’s Medical Center, USA

Abstract

Isolated medial longitudinal fasciculus (MLF) syndrome due to infarction limited only to the midbrain is a rare occurrence. The MLF are a group of fiber tracts located in the paramedian area of the midbrain and pons. They control horizontal eye movements by interconnecting oculomotor and abducens nuclei in the brain stem. Such small infarcts can easily be overlooked by young neuroradiologists and trainees. In this review, we discuss the clinical and imaging characteristics, comprehensive review of the anatomy, pathophysiology, and differential diagnosis.

Publisher

SAGE Publications

Subject

Neurology (clinical),Radiology, Nuclear Medicine and imaging,General Medicine

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