Brain positron emission tomography with 2-18F-2-deoxi-D-glucose of patients with dystonia and essential tremor detects differences between these disorders

Author:

Belenky Vadim1,Stanzhevsky Andrei2,Klicenko Olga3,Skoromets Alexandr4

Affiliation:

1. ‘Magia ruk’ Clinic, Russia

2. Central Radiology Institute, Russia

3. North-Western Medical University, Russia

4. First Pavlov State Medical University of St. Petersburg, Russia

Abstract

We studied patients with dystonia (D) and essential tremor (ET) using positron emission tomography (PET) equipped with Cortex ID software. This allowed PET brain visualisation to be compared to scans of a control group by means of the z-score. The study revealed hypo-metabolism in both D and ET groups, and additionally revealed a difference between these two groups of patients in certain areas of the brain. These two nosological forms overlap in clinical features and are difficult to differentiate. The PET picture may help to provide a differential diagnosis in addition to the biochemical difference in dopamine exchange previously revealed by us in this group of patients.

Publisher

SAGE Publications

Subject

Clinical Neurology,Radiology Nuclear Medicine and imaging,General Medicine

Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Tremor in cervical dystonia;Dystonia;2024-03-22

2. The role of laboratory investigations in the classification of tremors;Neurological Sciences;2023-10-10

3. [18F]FDG PET in conditions associated with hyperkinetic movement disorders and ataxia: a systematic review;European Journal of Nuclear Medicine and Molecular Imaging;2023-01-27

4. The functional anatomy of dystonia: Recent developments;International Review of Neurobiology;2023

5. PET and SPECT Imaging in Dystonia;PET and SPECT in Neurology;2020-10-11

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