Bioactive refinement for endosaccular treatment of intracranial aneurysms

Author:

Szatmary Zoltan12ORCID,Mounier Jérémy2,Janot Kevin23,Cortese Jonathan24,Couquet Claude2,Chaubet Frédéric56,Kadirvel Ramanathan7,Bardet Sylvia M2ORCID,Mounayer Charbel12,Rouchaud Aymeric12

Affiliation:

1. Department of Radiology, Dupuytren Hospital, Limoges University, France

2. XLIM UMR CNRS No. 7252, Limoges University, France

3. Regional University Hospital Center Tours, Radiology, Diagnostic and Interventional Neuroradiology, France

4. Bicêtre Hospital, Interventionnel Neuroradiology, Paris, France

5. Laboratory for Vascular Translational Science, UMRS 1148, INSERM, Université de Paris, France

6. Université Sorbonne Paris Nord- Campus de Bobigny, France

7. Mayo Clinic Rochester, Radiology, USA

Abstract

Endovascular treatment is the first-line therapy for most intracranial aneurysms; however, recanalisation remains a major limitation. Developments in bioengineering and material science have led to a novel generation of coil technologies for aneurysm embolisation that address clinical challenges of aneurysm recurrence. This review presents an overview of modified surface coil technologies and summarises the state of the art regarding their efficacy and limitations based on experimental and clinical results. We also present potential perspectives to develop biologically optimised devices.

Publisher

SAGE Publications

Subject

Clinical Neurology,Radiology Nuclear Medicine and imaging,General Medicine

Cited by 3 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Degrees of macrophage‐facilitated healing in aneurysm occlusion devices;Journal of Biomedical Materials Research Part B: Applied Biomaterials;2024-02

2. Fucoidan-coated coils improve healing in a rabbit elastase aneurysm model;Journal of NeuroInterventional Surgery;2023-07-25

3. FOXO1 represses MCL1 transcription to regulate the function of vascular smooth muscle cells in intracranial aneurysm;Experimental Brain Research;2022-09-14

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