Progressive Spinal Cord Compression Due to Epidural Extramedullary Hematopoiesis in Thalassemia Intermedia-Reference-Cited by-同舟云学术

Progressive Spinal Cord Compression Due to Epidural Extramedullary Hematopoiesis in Thalassemia Intermedia

Published:2013-02 Issue:1 Volume:26 Page:111-117
ISSN:1971-4009
Container-title:The Neuroradiology Journal
language:en
Short-container-title:Neuroradiol J

Author:

Ghieda U.¹,Elshimy M.¹,El Beltagi A. H.²

Affiliation:

1. Radiology Department, MOH-Kuwait, Al-Amiri Hospital; Sulaibikhat, Kuwait

2. Radiology Department, MOH-Kuwait, Al-Sabah Hospital; Sulaibikhat, Kuwait

Abstract

Extramedullary hematopoiesis (EMH) can occur in patients with thalassemia intermedia as a physiologic response to insufficient erythropoiesis to meet circulatory demands. Rarely, EMH involve the epidural space causing spinal cord compression. We describe a case of EMH in a 21-year-old man with β-thalassemia intermedia presenting with progressive low back pain, worsening paraparesis and sphincter disturbance. Magnetic resonance imaging (MRI) demonstrated spinal cord compression by EMH epidural mass lesions extending from T3 to T10 levels. An emergency multilevel decompressive laminectomy was performed with excision of the masses and complete rehabilitation of the patient.

Publisher

SAGE Publications

Subject

Clinical Neurology,Radiology Nuclear Medicine and imaging,General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/197140091302600119

Reference39 articles.

1. Spinal extradural hematopoiesis in adolescents with thalassemia

2. Paraplegia due to a paravertebral extramedullary haemopoiesis in a patient with polycythaemia vera

3. Extramedullary Hematopoiesis With Spinal Cord Compression in a Child With Thalassemia Intermedia

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