Radioimmunolocalization of Tumours by External Scintigraphy after Administration of 131I Antibody to Human Chorionic Gonadotrophin: Preliminary Communication-Reference-Cited by-同舟云学术

Radioimmunolocalization of Tumours by External Scintigraphy after Administration of 131I Antibody to Human Chorionic Gonadotrophin: Preliminary Communication

Published:1980-09 Issue:9 Volume:73 Page:624-630
ISSN:0141-0768
Container-title:Journal of the Royal Society of Medicine
language:en
Short-container-title:J R Soc Med

Author:

Begent R H J¹,Searle F¹,Stanway G¹,Jewkes R F¹,Jones B E¹,Vernon P¹,Bagshawe K D¹

Affiliation:

1. Departments of Medical Oncology and Nuclear Medicine Charing Cross Hospital, London W6 8RF

Abstract

131Iodine (131I) labelled antibody directed against human chorionic gonadatrophin (hCG) was given on 21 occasions to 18 patients with hCG-producing neoplasms. Tumours were localized by external scintigraphy in 13 of 21 investigations. Positive results were obtained reliably when serum hCG exceeded 500 miu/ml and in some cases sensitivity was comparable to that of computerized tomography. A positive result probably implies viability in the tumour and this was of practical value in discriminating between necrotic deposits and living tumour before surgery.

Publisher

SAGE Publications

Subject

General Medicine

Link

http://journals.sagepub.com/doi/pdf/10.1177/014107688007300905

Reference13 articles.

1. Bagshawe K D (1976) In: Medical Oncology, Ed. Bagshawe K D. Blackwell, Oxford; p 460

2. Localisation of tumour deposits by external scanning after injection of radiolabelled anti-carcinoembryonic antigen.

3. Use of Radiolabeled Antibodies to Carcinoembryonic Antigen for the Detection and Localization of Diverse Cancers by External Photoscanning

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